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M94A2580.TXT
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Document 2580
DOCN M94A2580
TI Trends in recent HIV-1 infection among patients at sentinel hospitals,
1988-1992.
DT 9412
AU Weber JT; Satten GA; Hanson DL; Schable CA; Janssen RS; CDC, Atlanta,
Georgia.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):271 (abstract no. PC0001). Unique
Identifier : AIDSLINE ICA10/94369995
AB OBJECTIVE: To use low beta 2-microglobulin (beta 2M) as a marker of
recent HIV-1 infection to estimate trends in recent HIV-1 infection in
communities served by 30 U.S. acute-care hospitals from 1988-1992.
METHODS: To collect a sample resembling the general U.S. adult
population, blood specimens were collected from an age- and
sex-stratified sample of patients > or = 15 years old with conditions
not associated with HIV-1. Specimens were tested anonymously for HIV-1
antibody; positive specimens were tested for beta 2M. beta 2M < 2.1 mg/L
(low beta 2M) was considered a marker for recent infection. We used
logistic regression to estimate trends in low beta 2M. RESULTS: Trends
in low beta 2-microglobulin among Sentinel Hospitals TABULAR DATA, SEE
ABSTRACT VOLUME. Predominant (> 50%) exposure category of AIDS cases
reported by hospital: male-male sex (MMS), injecting drug use (IDU), or
both. Some hospitals had no HIV-1 positive specimens among women.
DISCUSSION AND CONCLUSIONS: Incidence of HIV-1 infection among men, as
measured by low beta 2M, appears to be decreasing in many communities
served by sentinel hospitals, especially those that reported IDU as a
major exposure category for AIDS cases.
DE beta 2-Microglobulin/ANALYSIS Acquired Immunodeficiency
Syndrome/DIAGNOSIS/*EPIDEMIOLOGY Adult AIDS Serodiagnosis Biological
Markers/BLOOD Female Hospitals/*STATISTICS & NUMER DATA Human *HIV-1
Incidence Male Population Surveillance Risk Factors United
States/EPIDEMIOLOGY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).